Scaling Challenges and Solutions
October 1, 2026

Why Mission Matters: The Tech Humanist Podcast with Kate O'Neill

Why Mission Matters: The Tech Humanist Podcast with Kate O'Neill
# Team and Technical Agility
# State of AI
# SPC
# SAFe Practices
# SAFe Summit
# SAFe
# RTE
# Product Development Flow
# PI Planning
# Peer Networking
# Peer Learning
# Learning
# Discuss
# Customer Centricity
# Artificial Intelligence (AI)
# AI
# Agile Transformation
# Agile Leadership

Can mission-driven technology and AI truly work hand-in-hand to better serve humanity?

Why Mission Matters: The Tech Humanist Podcast with Kate O'Neill
Can mission-driven technology and AI truly work hand-in-hand to better serve humanity?
Join Kate O’Neill as she brings The Tech Humanist Show live to the SAFe & AI Summit with a compelling conversation featuring Lindsay Ann Wirthlin, who leads enterprise agile transformation at the American Red Cross.
Lindsay shares powerful stories about weaving technology into mission-driven work when every minute counts. Discover how the American Red Cross uses SAFe patterns and agile practices as the backbone for AI adoption and organizational change.
Topics Covered
  • Mission-driven technology at the Red Cross
  • The role of SAFe patterns in AI adoption
  • Prioritization in high-urgency organizations
  • Tackling change and adoption fatigue
  • Overcoming the human barriers to AI
  • Partnerships between Agile and AI teams
  • Measuring business value in technology transformation
  • Practical workshops for AI intake and adoption
  • Building trust and conflict resolution between teams
  • Success stories and the importance of scaffolding
  • The core of agile: people and relationships Episode Chapters 00:04 Introduction and context at the AI Summit 01:13 Mission-driven technology in action 02:17 Technology and the human experience at the Red Cross 03:34 What is SAFe and why it matters for leaders 04:06 Prioritization in urgent, mission-critical settings 05:21 Integrating AI: fears, realities, and professional impact 07:01 Navigating AI and Agile priorities 08:38 Signals & strategies for closing collaboration loops 09:42 Adoption fatigue and the human side of new tech 12:01 Bridging AI and organizational change management 13:17 Agile transformation as scaffolding for AI 15:28 From idea to outcome: real-world application of agile + AI 17:40 Forging practical partnerships between Agile COE and AI 19:11 Team linkages, intake models, and coaching 22:02 Decision-making boundaries and conflict resolution 24:23 Measuring effectiveness across teams 26:10 The AI intake problem-solving workshop 29:03 Lowering the adoption threshold: demos and use cases 32:15 AI coaches and bridging team learning 34:17 Tooling innovations for backlog management 35:55 Practices for Monday: inspect, adapt, and connect 38:04 The heart of transformation: people as scaffolding 39:39 Sources of hope and looking ahead 41:23 Closing remarks & credits
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